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1

Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

Li, Zhaoyang, Wang, Cen, Wang, Ziying, Zhu, Chenggang, Li, Jie, Sha, Tian, Ma, Lixiang, Gao, Chao, Yang, Yi, Sun, Yimin, Wang, Jian, Sun, Xiaoli, Lu, Chenqi, Difiglia, Marian, Mei, Yanai, Ding, Chen,

Journal:

Year:

2019

File:

PDF, 36.20 MB

2019

2

Large neurons in the primate neostriatum examined with the combined Golgi-electron microscopic method

Marian DiFiglia, Janice Carey

Journal:

The Journal of Comparative Neurology

Year:

1986

Language:

english

File:

PDF, 8.24 MB

english, 1986

3

Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients

Edith L. Pfister, Lori Kennington, Juerg Straubhaar, Sujata Wagh, Wanzhou Liu, Marian DiFiglia, Bernhard Landwehrmeyer, Jean-Paul Vonsattel, Phillip D. Zamore, Neil Aronin

Journal:

Current Biology

Year:

2009

Language:

english

File:

PDF, 244 KB

english, 2009

4

Early postnatal development of the monkey neostriatum: A Golgi and ultrastructural study

Marian Difiglia, Pedro Pasik, Tauba Pasik

Journal:

The Journal of Comparative Neurology

Year:

1980

Language:

english

File:

PDF, 8.13 MB

english, 1980

5

Ultrastructure of Golgi-impregnated and gold-toned spiny and aspiny neurons in the monkey neostriatum

Marian Difiglia, Tauba Pasik, Pedro Pasik

Journal:

Brain Cell Biology

Year:

1980

Language:

english

File:

PDF, 10.48 MB

english, 1980

6

Analysis of huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons

Martin, Eileen J., Kim, Manho, Velier, James, Sapp, Ellen, Lee, Hyun-Sook, Laforet, Genevieve, Won, Lisa, Chase, Kathy, Bhide, Pradeep G., Heller, Alfred, Aronin, Neil, Difiglia, Marian

Journal:

The Journal of Comparative Neurology

Year:

1999

Language:

english

File:

PDF, 923 KB

english, 1999

7

Basic Fibroblast Growth Factor Enhances the Growth of Postnatal Neostriatal GABAergic Neurons in Vitro

Dan Zhou, Marian DiFiglia

Journal:

Experimental Neurology

Year:

1993

File:

PDF, 1.97 MB

1993

8

Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures

Andrew Freese, Marian DiFiglia, Walter J. Koroshetz, M. Flint Beal, Joseph B. Martin

Journal:

Year:

1990

Language:

english

File:

PDF, 3.89 MB

english, 1990

9

A toxic mutant huntingtin species is resistant to selective autophagy

Fu, Yuhua, Wu, Peng, Pan, Yuyin, Sun, Xiaoli, Yang, Huiya, Difiglia, Marian, Lu, Boxun

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1019 KB

english, 2017

10

The correlation between excitatory amino acid-induced current responses and excitotoxicity in striatal cultures

Walter J. Koroshetz, Andrew Freese, Marian DiFiglia

Journal:

Year:

1990

Language:

english

File:

PDF, 721 KB

english, 1990

11

Evidence for synaptic proliferation, reorganization, and growth in the excitotoxic lesioned adult rat caudate nucleus

Rosalinda C. Roberts, Marian DiFiglia

Journal:

Experimental Neurology

Year:

1990

Language:

english

File:

PDF, 5.93 MB

english, 1990

12

Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers

Kimberly B. Kegel, Vitali Schewkunow, Ellen Sapp, Nicholas Masso, Erich E. Wanker, Marian DiFiglia, Wolfgang H. Goldmann

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 504 KB

english, 2009

13

Striatal Potassium Channel Dysfunction in Huntington's Disease Transgenic Mice

Ariano, Marjorie A., Cepeda, Carlos, Calvert, Christopher R., Flores-Hernández, Jorge, Hernández-Echeagaray, Elizabeth, Klapstein, Gloria J., Chandler, Scott H., Aronin, Neil, DiFiglia, Marian, Levine

Journal:

Journal of Neurophysiology

Year:

2005

Language:

english

File:

PDF, 1.04 MB

english, 2005

14

Cytochrome oxidase activity in the rat caudate nucleus: Light and electron microscopic observations

Marian Difiglia, Gerda A. Graveland, Leora Schiff

Journal:

The Journal of Comparative Neurology

Year:

1987

Language:

english

File:

PDF, 1.26 MB

english, 1987

15

A Golgi and ultrastructural study of the monkey globus pallidus

Marian Difiglia, Dr. Pedro Pasik, Tauba Pasik

Journal:

The Journal of Comparative Neurology

Year:

1982

Language:

english

File:

PDF, 2.33 MB

english, 1982

16

Neurobiotin™, a useful neuroanatomical tracer for in vivo anterograde, retrograde and transneuronal tract-tracing and for in vitro labeling of neurons

Qin Huang, Dan Zhou, Marian DiFiglia

Journal:

Journal of Neuroscience Methods

Year:

1992

Language:

english

File:

PDF, 6.89 MB

english, 1992

17

Immunoreactive calcium-binding protein (calbindin-D28k) in interneurons and trigeminothalamic neurons of the rat nucleus caudalis localized with peroxidase and immunogold methods

Neil Aronin, Kathryn Chase, Robin Folsom, Sylvia Christakos, Dr. Marian Difiglia

Journal:

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

18

Long-term survival of GABA-, enkephalin-, NADPH-diaphorase- and calbindin-d28k-containing neurons in fetal striatal grafts

Rosalinda C. Roberts, Marian DiFiglia

Journal:

Year:

1990

Language:

english

File:

PDF, 10.64 MB

english, 1990

19

IMMUNOCYTOCHEMICAL STUDY OF NEUROTENSIN LOCALIZATION IN THE MONKEY SPINAL CORD

Marian DiFiglia, Neil Aronin, Susan E. Leeman

Journal:

Annals of the New York Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 272 KB

english, 1982

20

Huntington Disease

G. Vonsattel, Jean Paul, DiFiglia, Marian

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1998

Language:

english

File:

PDF, 1.59 MB

english, 1998

21

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity

Yao, Yuwei, Cui, Xiaotian, Al-Ramahi, Ismael, Sun, Xiaoli, Li, Bo, Hou, Jiapeng, Difiglia, Marian, Palacino, James, Wu, Zhi-Ying, Ma, Lixiang, Botas, Juan, Lu, Boxun

Journal:

Year:

2015

Language:

english

File:

PDF, 4.53 MB

english, 2015

22

A Golgi study of the human neostriatum: Neurons and afferent fibers

Gerda A. Graveland, Roger S. Williams, Marian Difiglia

Journal:

The Journal of Comparative Neurology

Year:

1985

Language:

english

File:

PDF, 2.73 MB

english, 1985

23

Excitotoxic injury of the neostriatum: a model for Huntington's disease

Marian DiFiglia

Journal:

Trends in Neurosciences

Year:

1990

Language:

english

File:

PDF, 869 KB

english, 1990

24

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

Sheng, Rui, Zhang, Tong-Tong, Felice, Valeria D., Qin, Tao, Qin, Zheng-Hong, Smith, Charles D., Sapp, Ellen, Difiglia, Marian, Waeber, Christian

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.15 MB

english, 2014

25

Huntingtin-lowering strategies in Huntington's disease: Antisense oligonucleotides, small RNAs, and gene editing

Aronin, Neil, DiFiglia, Marian

Journal:

Movement Disorders

Year:

2014

Language:

english

File:

PDF, 195 KB

english, 2014

26

Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles

Haraszti, Reka Agnes, Miller, Rachael, Didiot, Marie-Cecile, Biscans, Annabelle, Alterman, Julia F., Hassler, Matthew R., Roux, Loic, Echeverria, Dimas, Sapp, Ellen, DiFiglia, Marian, Aronin, Neil, Kh

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

27

Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy

Kegel, Kimberly B., Kim, Manho, Sapp, Ellen, McIntyre, Charmian, Castaño, José G., Aronin, Neil, DiFiglia, Marian

Journal:

Journal of Neuroscience

Year:

2000

Language:

english

File:

PDF, 1.07 MB

english, 2000

28

Lysosomal proteases are involved in generation of N-terminal huntingtin fragments

Yun J. Kim, Ellen Sapp, Benjamin G. Cuiffo, Lindsay Sobin, Jennifer Yoder, Kimberly B. Kegel, Zheng-Hong Qin, Peter Detloff, Neil Aronin, Marian DiFiglia

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 472 KB

english, 2006

29

Intrastriatal Injections of Quinolinic Acid or Kainic Acid: Differential Patterns of Cell Survival and the Effects of Data Analysis on Outcome

Rosalinda C. Roberts, Andrew Ahn, Kenton J. Swartz, M.Flint Beal, Marian DiFiglia

Journal:

Experimental Neurology

Year:

1993

File:

PDF, 824 KB

1993

30

Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity

Zhong-Qin Liang, Xiao-Xia Wang, Yumei Wang, De-Maw Chuang, Marian DiFiglia, Thomas N. Chase, Zheng-Hong Qin

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 1.12 MB

english, 2005

31

Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington’s disease mice

McClory, Hollis, Williams, Dana, Sapp, Ellen, Gatune, Leah W, Wang, Ping, DiFiglia, Marian, Li, Xueyi

Journal:

Acta Neuropathologica Communications

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

32

Immunohistochemical Localization of the D1Dopamine Receptor in Rat Brain Reveals its Axonal Transport, Pre- and Postsynaptic Localization, and Prevalence in the Basal Ganglia, Limbic, System and Thalamic Reticular Nucleus

Qin Huang, Dan Zhou, Kathy Chase, James F. Gusella, Neil Aronin and Marian DiFiglia

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.37 MB

english, 1992

33

High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources

Haraszti, Reka A., Didiot, Marie-Cecile, Sapp, Ellen, Leszyk, John, Shaffer, Scott A., Rockwell, Hannah E., Gao, Fei, Narain, Niven R., DiFiglia, Marian, Kiebish, Michael A., Aronin, Neil, Khvorova, A

Journal:

Journal of Extracellular Vesicles

Year:

2016

Language:

english

File:

PDF, 3.36 MB

english, 2016

34

Colocalization of D1 and D2 dopamine receptor mRNAs in striatal neurons

John Lester, Stephen Fink, Neil Aronin, Marian DiFiglia

Journal:

Year:

1993

Language:

english

File:

PDF, 779 KB

english, 1993

35

Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?

Stephen W Davies, Kathryn Beardsall, Mark Turmaine, Marian DiFiglia, Neil Aronin, Gillian P Bates

Journal:

Year:

1998

Language:

english

File:

PDF, 497 KB

english, 1998

36

Safety of Striatal Infusion of siRNA in a Transgenic Huntington’s Disease Mouse Model

Johnson, Emily, Chase, Kathryn, McGowan, Sarah, Mondo, Erica, Pfister, Edith, Mick, Eric, Friedline, Randall H., Kim, Jason K., Sapp, Ellen, DiFiglia, Marian, Aronin, Neil

Journal:

Journal of Huntington's Disease

Year:

2015

Language:

english

File:

PDF, 267 KB

english, 2015

37

The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival

McClory, Hollis, Wang, Xiaolong, Sapp, Ellen, Gatune, Leah W., Iuliano, Maria, Wu, Chiu-Yi, Nathwani, Gina, Kegel-Gleason, Kimberly B., DiFiglia, Marian, Li, Xueyi

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.97 MB

english, 2018

38

Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin

Didiot, Marie-Cécile, Ferguson, Chantal M., Ly, Socheata, Coles, Andrew H., Smith, Abigail O., Bicknell, Alicia A., Hall, Lauren M., Sapp, Ellen, Echeverria, Dimas, Pai, Athma A., DiFiglia, Marian, Mo

Journal:

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

39

Ultrastructural localization of immunoreactive neurotensin in the monkey superficial dorsal horn

Marian Difiglia, Neil Aronin, Susan E. Leeman

Journal:

The Journal of Comparative Neurology

Year:

1984

Language:

english

File:

PDF, 1.65 MB

english, 1984

40

Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity

Andrew Freese, Seth P. Finklestein, Marian DiFiglia

Journal:

Year:

1992

Language:

english

File:

PDF, 2.55 MB

english, 1992

41

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W Davies, Mark Turmaine, Barbara A Cozens, Marian DiFiglia, Alan H Sharp, Christopher A Ross, Eberhard Scherzinger, Erich E Wanker, Laura Mangiarini, Gillian P Bates

Journal:

Year:

1997

Language:

english

File:

PDF, 982 KB

english, 1997

42

Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.

Fox, Jonathan H., Connor, Teal, Stiles, Megan, Kama, Jibrin, Lu, Zhen, Dorsey, Kathryn, Lieberman, Gregory, Sapp, Ellen, Cherny, Robert A., Banks, Mary, Volitakis, Irene, DiFiglia, Marian, Berezovska,

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

43

Neuronal high-affinity glutamate transport in the rat central nervous system

Kanai, Yoshikatsu, Bhide, Pradeep G., DiFiglia, Marian, Hediger, Matthias A.

Journal:

Year:

1995

File:

PDF, 500 KB

1995

44

Huntingtin is degraded to small fragments by calpain after ischemic injury☆

Manho Kim, Jae-Kyu Roh, Byung Woo Yoon, Lami Kang, Yun J Kim, Neil Aronin, Marian DiFiglia

Journal:

Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

45

Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair

Rubinsztein, David C., DiFiglia, Marian, Heintz, Nathaniel, Nixon, Ralph A., Qin, Zheng-Hong, Ravikumar, Brinda, Stefanis, Leonidas, Tolkovsky, Aviva

Journal:

Year:

2005

Language:

english

File:

PDF, 289 KB

english, 2005

46

Localization of immunoreactive GABA and enkephalin and NADPH-Diaphorase-positive neurons in fetal striatal grafts in the quinolinic-acid-lesioned rat neostriatum

Rosalinda C. Roberts, Marian Difiglia

Journal:

The Journal of Comparative Neurology

Year:

1988

Language:

english

File:

PDF, 2.22 MB

english, 1988

47

Wild-Type and Mutant Huntingtins Function in Vesicle Trafficking in the Secretory and Endocytic Pathways

James Velier, Manho Kim, Cordula Schwarz, Tae Wan Kim, Ellen Sapp, Kathryn Chase, Neil Aronin, Marian DiFiglia

Journal:

Experimental Neurology

Year:

1998

Language:

english

File:

PDF, 1.81 MB

english, 1998

48

A Golgi study of neuronal types in the neostriatum of monkeys

Marian DiFiglia, Pedro Pasik, Tauba Pasik

Journal:

Year:

1976

Language:

english

File:

PDF, 3.48 MB

english, 1976

49

Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance

Lu, Boxun, Al-Ramahi, Ismael, Valencia, Antonio, Wang, Qiong, Berenshteyn, Frada, Yang, Haidi, Gallego-Flores, Tatiana, Ichcho, Salah, Lacoste, Arnaud, Hild, Marc, DiFiglia, Marian, Botas, Juan, Palac

Journal:

Nature Neuroscience

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

50

Fast transport and retrograde movement of huntingtin and HAP 1 in axons

Block-Galarza, Jessie, Chase, Kathryn O., Sapp, Ellen, Vaughn, Kevin T., Vallee, Richard B., DiFiglia, Marian, Aronin, Neil

Journal:

Year:

1997

Language:

english

File:

PDF, 707 KB

english, 1997

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